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TROPONIN C1
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DeCS
Descriptor
English
:
Troponin C
Descriptor
Spanish
:
Troponina C
Descriptor
Portuguese
:
Troponina C
Synonyms
English
:
Troponin C1
Troponin C2
Troponin-C
Tree Number:
D05.500.945.900
D05.750.078.730.825.900
D12.776.157.125.900
D12.776.210.500.910.900
D12.776.220.525.825.900
Definition
English
:
A
TROPONIN
complex subunit that binds
calcium
and help regulate calcium-dependent
muscle contraction
. There are two
troponin C
subtypes:
troponin
C1 and C2.
Troponin
C1 is skeletal and cardiac type whereas
troponin
C2 is skeletal type.
Troponin
C1 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and
mutations
in
troponin
C1 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Indexing Annotation
English
:
TROPONIN I
&
TROPONIN T
are also available
History Note
English
:
97; was TROPONIN C (NM) 1975-96
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33042
Unique Identifier:
D019209
Occurrence in VHL
:
Similar:
DeCS